Search results for "Parathyroid adenoma"
showing 5 items of 5 documents
Parathyroid hormone is inversely related to endothelin-1 in patients on haemodialysis
2008
SUMMARY: Aim: Parathyroid hormone secretion is mainly influenced by hypocalcaemia, hyperphosphataemia and vitamin D deficiency. However, previous in vitro and in vivo studies showed that endothelin-1 can influence parathyroid hormone secretion. This study was aimed at evaluating this relationship in vivo in uraemic patients. Methods: Parathyroid hormone and endothelin-1 plasma concentrations were measured in 67 haemodialysed patients. Patients with history of cardiovascular diseases and those with parathyroid adenoma were excluded. Results: Plasma levels of endothelin-1 were found to be inversely related to those of parathyroid hormone (P < 0.04) The multiple regression analysis, carried ou…
Short Ammonium Chloride Loading Test for Evaluation of Hyperparathyroidism
1981
The dilemma in the diagnosis of hyperparathyroidism (HPT) is reflected by three factors: Hypercalcemia is still regarded as the most important diagnostic sign, but unless multiple determinations of serum calcium are done, the so-called borderline cases will be missed. Tests that readily identify HPT combine either simple performance, widespread use and low accuracy (CP, TRP, PEI, TMP/GFR)l or sophisticated methods, limited use and high accuracy (PTH, Ca+++, c-AMP). Consequently, some authors perform neck explorations to cure patients with recurrent nephrolithiasis who do not fulfill the diagnostic criteria of HPT. However, the stone recurrence rate may then reach 75%2,3 In this situation, t…
Contrast-Enhanced Ultrasound Qualitative and Quantitative Characteristics of Parathyroid Gland Lesions
2021
Background and Objectives: preoperative differentiation of enlarged parathyroid glands may be challenging in conventional B-mode ultrasound. The aim of our study was to analyse qualitative and quantitative characteristics of parathyroid gland lesions, using multiparametric ultrasound protocol—B-mode, Colour Doppler (CD), and contrast-enhanced ultrasound (CEUS)—and to evaluate correlation with morphology in patients with hyperparathyroidism (HPT). Materials and Methods: consecutive 75 patients with 88 parathyroid lesions and biochemically confirmed HPT prior to parathyroidectomy were enrolled in the prospective study. B-mode ultrasound, CD, and CEUS were performed with the subsequent qualita…
The role of combined techniques of scintigraphy and SPECT/CT in the diagnosis of primary hyperparathyroidism
2019
RATIONALE Primary hyperparathyroidism, usually as a result of a hyperfunctioning parathyroid gland, represents more than 90% cases of patients evaluated for hypercalcemia. Combined techniques of preoperative scintigraphy and SPECT/CT serve as a successful minimally-invasive parathyroidectomy. This recent imaging method provides four-dimensional functional images with advanced contrast resolution which greatly facilitates preoperative localization of parathyroid adenomas. PATIENT CONCERNS We presented the case of a male Caucasian patient, aged 67 years, who was investigated for hypercalcemia. Increased levels of parathormone, cervical ultrasonography without pathological changes, and negativ…
Non-functioning parathyroid cystic tumour: malignant or not? Report of a case
2017
Parathyroid carcinoma (PC) is a very rare endocrine tumour, usually characterized by symptoms such as a neck mass, dysphonia, severe hypercalcemia exceeding 140 mg/L and elevated serum parathyroid hormone levels, even more than 5 times the upper limit of normal. Non-functioning parathyroid cancer is extremely rare and, in this case, its pre-operative diagnosis is often difficult. A 54-year old female patient, referring dysphagia and dysphonia, underwent neck ultrasound and neck CT. A left thyroid nodule, probably cystic, was found. It presented caudal extent on anterior mediastinum causing compression of the left lateral wall of the trachea. The preoperative calcemia was into the normal ran…